Receptors against autoimmunity
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چکیده
منابع مشابه
Angiotensin receptors, autoimmunity, and preeclampsia.
Preeclampsia is a pregnancy-induced hypertensive disorder that causes substantial maternal and fetal morbidity and mortality. Despite being a leading cause of maternal death and a major contributor to maternal and perinatal morbidity, the mechanisms responsible for the pathogenesis of preeclampsia are poorly understood. Recent studies indicate that women with preeclampsia have autoantibodies th...
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Heterotrimeric G proteins can be divided into Gi, Gs, Gq/11, and G12/13 subfamilies according to their α subunits. The main function of G proteins is transducing signals from G protein coupled receptors (GPCRs), a family of seven transmembrane receptors. In recent years, studies have demonstrated that GPCRs interact with Gq, a member of the Gq/11 subfamily of G proteins. This interaction facili...
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19. Wells, J.. Isbister, J. & Kies, C. (1987) in Basic and Clinical Immunology (Stites, D., Stobo, J. & Wells, J.. eds.). 6th edn, pp. 405-416, Appleton Lange. London Rose, N., Lorenzi, M. & Lewis, M. (1987) in Basic and Clinical Immunology (Stites, P., Stobo. J. & Wells, J., eds.), 6th edn, pp. 582-598, Appleton Lange, London Coombs, S. & Gel, P. (1975) in Clinical Aspects of Immunology (Gel, ...
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Long-term depressive behavior was modeled via immunization of white rats with isatin (an endogenous MAO inhibitor) covalently bound to a carrier antigen. The immunization of rats against isatin and several exogenous MAO inhibitors (pargyline and deprenyl) resulted in long-term (2 months) depressive-like behavior with elements of anxiety and an increased activity of MAO in the brain. In contrast...
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Receptor tyrosine kinases, Tyro-3, Axl and Mer, collectively designated as TAM, are involved in the clearance of apoptotic cells. TAM ligands, Gas6 and Protein S, bind to the surfaces of apoptotic cells, and at the same time, interact directly with TAM expressed on phagocytes, impacting the engulfment and clearance of apoptotic cells and debris. The well-tuned and balanced actions of TAM may af...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 2007
ISSN: 1540-9538,0022-1007
DOI: 10.1084/jem.2042iti4